BEC Research interests (T7)

Key words

Natural products, ageing, valorization, analytical chemistry, biochemistry, biotechnology, chemometrics


Research Themes

The principal axes are :
• the development of a global vision of the conservation of natural resources mainly of the microbial and vegetable biomass (aromatic and medicinal plants, essential oil, vegetable oil, honeys, saffron yellow) of the island and conti-nental ecosystems,
• the characterization and the forecast of the dynamics of the ecosystems in front of global changes (climate, demog-raphy) with the aim of their sustainable management and to highlight regional soil effects,
• the identification of metabolomics indicators through the chemometrics treatments of the data (chromatographic and/or spectroscopic) allowing to study the dynamics of the ecosystems and the services which they return to soci-eties to anticipate breaking points
• the implementation of innovative practices (biorefineries) for productive and resilient ecosystems with the aim of giving answers to the major societal issues, among which the food quality and the biocontrol. In this context, myco-toxin degradation is a major stake for the food self-sufficiency, but also the replacement of chemical pesticides by biopesticides or the study of the natural or feigned ageings of natural or formulated products.
• the degradation or sequestration (storage) of recalcitrant organic compounds or natural or anthropological miner-als contaminating the environment with the objective to protect the ecosystems.
• the isolation and characterization of secondary metabolites with the aim to valuate natural resources.
• The morphological , cellular and molecular characterization of organisms of interest through different microscopic techniques (scanning and transmission electronic miscroscope, confocal microscopy)
The ambition of the team is to aggregate the scientific knowledge produced by its members and to incite and to stimulate the interfaces between them in order to favor interdisciplinary approaches among IMBE and with our southern partners. The members of the team collaborate within networks concerned by all the natural and man-impacted terrestrial and aquatic biomes, constituting the biodiversity of the continental and insular agricultural systems of the Mediterranean and tropical areas

Programms

Sartorius Stedim FMT

The use of single-use device in biopharmaceutical and biotechnological industries has become rather common nowadays. These devices are made from multilayer films, which can consist of polyethylene (PE), ethylene vinyl acetate (EVA) and ethylene vinyl alcohol (EVOH). These polymers are used for their flexibility and barrier properties. For future use, these devices must be sterilized. γ-irradiation is the most widely used sterilization process because of it high penetrating power. Ionizing radiation effects on polymers have been widely investigated. Chemical and physical properties of single-use plastic bag under γ-rays exposure can undergo changes. These types of changes depend on many factors, such as the type of plastic materials (chemical structure and morphology of polymer), specific additives used inside the plastic, radiation dose and the irradiation atmosphere. It is well known that the main effect of the interaction of γ-rays with polymers is the formation of free radicals, whose further evolution can cause scission and/or cross-linking events and among other things : release of gases, discoloration, changes in mechanical properties and gas permeability, degradation and leaching of polymer additives into solvents. All these aspects will be studied.

TeaM Cables

TeaM Cables – European Tools and Methodologies for an efficient ageing management of nuclear power plant Cables – is a research project in the field of nuclear safety and long-term operation. Launched in September 2017, the project has received a funding of 4.2 million Euro from the Horizon 2020 Euratom Research and Training Programme 2014-2018 of the European Union. It is set to run for a period of 54 months and is coordinated by Electricité de France (EDF).
TeaM Cables will develop a novel multiscale approach for more precise estimation of the cable lifetime. The project will analyse the effects of irradiation and temperatures on cables from micro- to macroscale level, in order to develop multiscale models of ageing. Ageing in normal operation conditions and accidental conditions will be addressed. The unique multi-scale and kinetic models produced by the project will be integrated into an open access tool – the TeaM Cables tool – which will be built on the merger of a currently used European cable management tool with a cable ageing modelling tool. In parallel, criteria and protocols for on-site use of non-destructive testing techniques will be proposed.