Serge Champion

Professeur 1° Classe Emérite

Institut Méditerranéen de Biodiversité et d’Écologie Marine et Continentale (IMBE)
UMR IMBE | Aix Marseille Université, CNRS, IRD, Avignon Université

Campus Timone
Faculté de Pharmacie
27 bd Jean Moulin
13385 MARSEILLE Cedex 05
France

Equipe Biodiversité , Environnement , Santé (BES) Pharmacie

Courriel : serge.champion@univ-amu.fr

Publications

Sreng N, Champion S, Martin JC, Khelaifia S, Christensen JE, Padmanabhan R, Azalbert V, Blasco-Baque V, Loubieres P, Pechere L, Landrier J-F, Burcelin R, Seree E 2019 Resveratrol-mediated glycemic regulation is blunted by curcumin and is associated to modulation of gut microbiota. J Nutr Biochem. 72:108218, doi: 10.1016/j.jnutbio.2019.108218

HAL

May P, Bremond P, Sauzet C, Piccerelle P, Grimaldi F, Champion S, Villard P-H 2018 In vitro cocktail effects of PCB-DL (PCB118) and Bulky PCB (PCB153) with BaP on adipogenesis and on expression of genes involved in the establishment of a pro-inflammatory state. International Journal of Molecular Sciences 19:841, doi: 10.3390/ijms19030841

HAL

Mesnier A, Champion S, Louis L, Sauzet C, May P, Portugal H, Benbrahim K, Abraldes J, Alessi M-C, Amiot-Carlin M-J, Peiretti F, Piccerelle P, Nalbone G, Villard P-H 2015 The Transcriptional Effects of PCB118 and PCB153 on the Liver, Adipose Tissue, Muscle and Colon of Mice: Highlighting of Glut4 and Lipin1 as Main Target Genes for PCB Induced Metabolic Disorders. PLOS ONE 10(6):e0128847, doi: 10.1371/journal.pone.0128847

HAL

Njock M-S, Fouchier F, Seree E, Villard P-H, Landrier J-F, Pechere L, Barra Y, Champion S 2014 Lycopene Modulates THP1 and Caco2 Cells Inflammatory State through Transcriptional and Nontranscriptional Processes. Mediators Inflamm. 2014:507272, doi: 10.1155/2014/507272

HAL

Champion S, Sauzet C, Brémond P, Benbrahim K, Abraldes J, Seree E, Barra Y, Villard P-H 2013 Activation of the NF kappa B Pathway Enhances AhR Expression in Intestinal Caco-2 Cells. ISRN Toxicology 2013:792452, doi: 10.1155/2013/792452

HAL

Dao T-M A, Waget A, Klopp P, Serino M, Vachoux C, Pechere L, Drucker D, Champion S, Barthelemy S, Barra Y, Burcelin R, Seree E 2011 Resveratrol Increases Glucose Induced GLP-1 Secretion in Mice: A Mechanism which Contributes to the Glycemic Control. PLOS ONE 6(6): e20700, doi: 10.1371/journal.pone.0020700

HAL

Villard P-H, Barlesi F, Armand M, Dao, T-M A, Pascussi J-M, Fouchier F, Champion S, Dufour C, Ginies C, Khalil A, Amiot M-J, Barra Y, Seree E 2011 CYP1A1 Induction in the Colon by Serum: Involvement of the PPAR alpha Pathway and Evidence for a New Specific Human PPRE alpha Site. PLOS ONE 6(1):e14629, doi: 10.1371/journal.pone.0014629

HAL

Nakbi A, Dabbou S, Champion S, Fouchier F, Mehri S, Attia N, Leger C, Hammami M 2011 Modulation of the superoxide anion production and MMP-9 expression in PMA stimulated THP-1 cells by olive oil minor components: Tyrosol and hydroxytyrosol. Food Research International 44(2):575-581, doi: 10.1016/j.foodres.2010.12.010

HAL

Ayman K, Villard P-H, Dao M A, Burcelin R, Champion S, Fouchier F, Savouret J-F, Barra Y, Seree E 2010 Polycyclic aromatic hydrocarbons potentiate high-fat diet effects on intestinal inflammation. Toxicology Letters 196(3):161-167, doi: 10.1016/j.toxlet.2010.04.010

HAL

Fouchier F, Penel C, Montero M-P, Brémond P, Champion S 2007 Integrin alphav beta6 mediates HT29-D4 cell adhesion to MMP-processed fibrinogen in the presence of Mn2+. Eur J Cell Biol 86(3):143-160, doi: 10.1016/j.ejcb.2006.12.002

HAL

Seree E, Villard P-H, Pascussi JM, Pineau T, Maurel P, Nguyen QB, Fallone F, Martin PM, Champion S, Lacarelle B, Savouret JF, Barra Y 2004 Evidence for a new human CYP1A1 regulation pathway involving PPAR-alpha and 2 PPRE sites. Gastroenterology 127(5):1436-1445, doi: 10.1053/j.gastro.2004.08.023

HAL

Vallee S, Laforest S, Fouchier F, Montero M-P, Penel C, Champion S 2004 Cytokine-induced upregulation of NF-kappaB, IL-8, and ICAM-1 is dependent on colonic cell polarity: implication for PKCdelta. Exp Cell Res. 297(1):165-85, doi: 10.1016/j.yexcr.2004.03.007

HAL

Vallee S, Fouchier F, Brémond P, Briand C, Marvaldi J, Champion S 2003 Insulin-like growth factor-1 downregulates nuclear factor kappa B activation and upregulates interleukin-8 gene expression induced by tumor necrosis factor alpha. Biochemical and Biophysical Research Communications 305(4):831-839, doi: 10.1016/S0006-291X(03)00866-0

HAL

Berthet V, Rigot V, Champion S, Secchi J, Fouchier F, Marvaldi J, Luis J 2000 Role of endoproteolytic processing in the adhesive and signaling functions of alpha(v)beta(5) integrin. Journal of Biological Chemistry 275(43):33308-33313, doi: 10.1074/jbc.M004834200

HAL

Mirrione A, Mauchamp J, Rimet O, Roccabianca M, Barra Y, Alquier C, Champion S 2000 Follicle-like structures formed by intestinal cell lines derived from the HT29-D4 adenocarcinoma cell line: morphological and functional characterization. Biol Cell. 91(2):143-55, doi: 10.1016/s0248-4900(99)80038-0

HAL