Morgane Mauduit

PhD Student

Team 5 DFME : Diversité et Fonctionnement des Molécules aux Ecosystèmes

Institut Méditerranéen de Biodiversité et d’Écologie Marine et Continentale (IMBE)
UMR IMBE | Aix Marseille Université, CNRS, IRD, Avignon Université

Station Marine d’Endoume, Rue de la Batterie des Lions, 13007 Marseille, France

morgane.mauduit@imbe.fr

https://twitter.com/M0rgane_PhD

Biosketch

A chemist in the middle of the sea

Young scientist passionate about multi-disciplinary researches, I am carrying out a PhD combining chemistry, the valorization of marine natural products in drug-discovery and marine chemical ecology. My PhD is dedicated to the chemical investigations and biological valorization of sponge metabolites naturally released in seawater. I am particularly motivated by the valorization of natural products to fight multi-drugs resistant bacteria (MDR) and re-emerging diseases, such as flavivirus.
Beside my PhD work, I also enjoy participating in outreach activities sensitizing the young generation to better knowledge of the marine world.

PhD subject

In the context of the ANR SESAM (coord. Charlotte Simmler), my PhD subject is untitled : Capture of sponge exo-metabolites, chemical characterization and evaluation of their anti-microbials properties. I am supervised by Charlotte Simmler and Thierry Pérez.

Key words

Exo-metabolites, marine sponges, marine natural products, chemical ecology

CV

Professional Experiences

Since Nov. 2020 : PhD student in marine natural products
Subject : “Capture of sponge exo-metabolites, chemical characterization and evaluation of their anti-microbials properties”
Supervisors : Thierry Pérez and Charlotte Simmler. 80 Primes CNRS MITI fellowship.

2020 : Research internship
Subject : “Optimizing the capture of Aplysina cavernicola exo-metabolites by solid phase adsorption”
Supervisors : Charlotte Simmler, Stéphane Greff and Thierry Pérez
Laboratory : Mediterranean Institute of Terrestrial and Marine Biodiversity and Ecology (IMBE)

2018 – 2019 : European Volunteering Service
In charge of the Eko-Patrola program : Scientific mediation and non-formal education for local children.
Organization : Udruga Argonauta. Island of Murter, Croatia.
https://argonauta.hr/en/

2018 : Engineer internship
Subject : “Development of biocompatible hydrogel fibres using wet-spinning technique and application in 3D printing”
Supervisors : Anaïs Chalard and Pierre Joseph
Laboratory : Laboratory for Analysis and Architecture of Systems (LAAS-CNRS).
Research group : Micro-Nanofluidics for Life science and Environment (MILE). Toulouse, France.

Education

2014 – 2020 : Engineer in Chemistry – Master’s degree in Chemistry
Ecole Supérieure de Chimie Organique et Minérale (ESCOM). Compiègne, France.

Thanks

I would like to deeply thanks all the advisors and teachers who shared and transmitted me theirs passions for sciences and researches.

Publications et communications orales

Communications

2021 : Journées du GDR MediaTEC (Ecologie Chimique). Toulouse, France.
Oral communication : « Access the diversity of molecules naturally released by sponges : Exo-metabolites, Catch them (all) ! » M. Mauduit, S. Greff, T. Pérez, C. Simmler

2021 : XII European Conference on Marine Natural Products (ECMNP). Galway, Ireland (on-line).
Poster : « Exploring the diversity of brominated alkaloids naturally released by the sponge Aplysina cavernicola » M. Mauduit, S. Greff, T. Pérez, C. Simmler

2022 : METABIODIVEX : Molecular Exploration of Biodiversity : new challenges, new strategies . Aussois, France.
Poster : « Diving into the chemistry of sponge exo-metabolomes : contribution of brominated specialized metabolites » M. Mauduit, S. Greff, T. Pérez, C. Simmler
Best poster award

Congress & Thematic School

2022 : Global Young Scientits Summit. International, online.

2022 : First European School of Metabolomics. International, Moustiers-Sainte-Marie, France.

2022 : METABIODIVEX : Molecular Exploration of Biodiversity : new challenges, new strategies . Aussois, France.

Publications

2020 : 3D printing of a biocompatible low molecular weight supramolecular hydrogel by dimethylsulfoxide water solvent exchange", A. Chalard, M. Mauduit, S. Souleille, P. Joseph, L. Malaquin, J. Fitremann, Additive Manufacturing https://doi.org/10.1016/j.addma.2020.101162.